Image Analysis Group (UK) is a leader in the rapidly growing market for Magnetic Resonance Imaging (MRI) data quantification and analysis, helping partners such as hospitals, CROs and biotech companies design and manage their clinical studies for the most effective use of resources while providing earlier, more convincing evidence of treatment effect with smaller patient cohorts. The company's solution improves the accuracy of diagnostic assessment and research decisions for companies developing treatments for inflammatory musculoskeletal conditions, neuro-inflammation, oncology, cardiac perfusion and rare diseases.
Immusoft (Seattle, USA) develops a first-in-class hybrid cell/gene therapy, which uses a clinically validated, non-viral vector for safe, reliable insertion of functional genes into B-cells. The ISP™ platform enables safe insertion of genes encoding the correct human homolog of a missing or defective protein into a patient’s immune cells using the Sleeping Beauty (SB) Transposon system – a non-viral vector. If successful, the therapy could become a breakthrough in multiple indications with lysosomal storage and protein production disorders.
AGCT (St. Petersburg, Russia) develops a gene therapy against HIV and HIV-linked cancers. The setup is a spin-out from one of the major oncology clinics in Russia and is supported by IP on genome editing from a top EU university. The therapy has the potential to bring cure to previously incurable patients with HIV and lymphomas and could also be used in a number of less severe indications.
Pipeline Therapeutics a US-based creating a portfolio of first-in-class small molecules in neuro-regeneration: Synaptogenesis (with a lead program in Hearing Loss), Remyelination, and Axonal Repair. PIPE-505 is the first small molecule developed specifically for the treatment of sensorineural hearing loss (SNHL) associated with cochlear synaptopathy. The therapeutic focus, regeneration of the cochlear synapse, should augment signal-to-noise processing and manifest as improved speech-in-noise comprehension, a chief auditory complaint and unmet need of patients with SNHL.
Botkin.AI is a leading developer of medical solutions based on a proprietary platform using artificial intelligence technologies. The products developed by the company facilitate the identification and analysis of pathologies in computer tomography, X-ray and mammography images. The use of Botkin.AI allow to improve early diagnosis of various diseases and increase the efficiency of physicians’ work.
PanDx (Cambridge, UK) develops a catheter for the treatment of acute pancreatitis and other severe GI conditions. By combining a number of novel and established treatment approaches, the catheter is positioned to significantly decrease mortality and reduce the treatment costs, as well as discover new ways of diagnosing diverse hepato-biliary diseases.